Determination of valsartan drug by ion pair complex formation method in tablet form

Authors

  • Qaaed Baker Ministry of Education Author
  • Eman Thiab Al-Samarrai University of Samarra Author

DOI:

https://doi.org/10.69923/851hfy94

Keywords:

Ion pair ,Pharmaceutical ,Spectrophotometer, Tablets, Valsartan

Abstract

A rapid, simple, sensitive, spectroscopic, ion pair complex method was developed for valsartan (VAL ) in pharmaceutical forms. Resazurin dye was used to form an ion pairing complex with the drug valsartan. analytical characteristics of the proposed method are Beer’s law range =10-60 (μg/mL), correlation coefficient  (R2) = 0.9976 , limit of detection (LOD) = 0.1076(µg/mL), limit of quantification (LOQ) = 0.3261 (µg/mL), recovery percentage (%Rec) = (101.9626% - 95.6074%), relative standard deviation (%RSD)= 0.6188% - 0.7148%, Molar absorption (ε)= 4659.85(L/mol.cm), Sandell's index(S) = 0.093458(μg/cm2),at wavelength 495 nm . The results showed high accuracy and precision of the proposed quantification method for the valsartan drug , and it was of high accuracy and consistent.

Downloads

Download data is not yet available.

Author Biographies

  • Qaaed Baker, Ministry of Education

     Qaaed Baker Ali    Master's student in the Chemistry Department, Collage of Education, Samarra University. His research areas are in the field of analytical chemistry and how to estimate medical drugs. One research was published in a journal within the Scopus archives, and another research was published in a conference indexed within the Scopus conferences. He received a letter of thanks from the President of the University of Samara. He can be contacted at email: qaed_ali@uosamarra.edu.iq

  • Eman Thiab Al-Samarrai, University of Samarra

    Dr. Eman Thiab Al-Samarrai is an Associate Professor at the College of Education, University of Samarra, Iraq. She received a B.Sc. degree in Chemistry from the University of Samarra and an M.Sc. degree from the University of Samarra. Her research areas are in the field of analytical chemistry and how to estimate medical drugs. She has published many scientific papers in national and international conferences and journals. She can be contacted at emil: eman.dh@uosamarra.edu.iq

Downloads

Published

09/30/2024

Issue

Vol. 1 No. 2 (2024)

Section

Articles

License

Copyright (c) 2024 Iraqi Journal for Applied Sciences

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Licenses and Copyright

The following policy applies to the Iraqi Journal of Sciences (IJAS).

  1. IJAS applies Creative Commons Attribution (CC BY) license
  2. If you have written permission to do so, yes. If your manuscript contains content such as photos, images, figures, tables, audio files, videos, etc., that you or your co-authors do not own, we will require you to provide us with proof that the owner of that content (a) has given you written permission to use it, and (b) has approved of the CC BY license being applied to their content. We provide a form you can use to ask for and obtain permission from the owner. If you do not have owner permission, we will ask you to remove that content and/or replace it with other content that you own or have such permission to use. Don't assume that you can use any content you find on the Internet, or that the content is fair game just because it isn't clear who the owner is or what license applies. It's up to you to ascertain what rights you have” if any” to use that content.
  3. Many authors assume that if they previously published a paper through another publisher, they own the rights to that content and can freely use that content in their PLOS paper, but that is not necessarily the case; it depends on the license that covers the other paper. Some publishers allow free and unrestricted re-use of article content they own, such as under the CC BY license. Other publishers use licenses that allow re-use only if the same license is applied by the person or publisher re-using the content. If the paper was published under a CC BY license or another license that allows free and unrestricted use, you may use the content in your IJS paper provided that you give proper attribution, as explained above. If the content was published under a more restrictive license, you must ascertain what rights you have under that license. At a minimum, review the license to make sure you can use the content. Contact IJAS if you have any questions about the license. If the license does not permit you to use the content in a paper that will be covered by an unrestricted license, you must obtain written permission from the publisher to use the content in your IJSPlease do not include any content in your IJAS paper that you do not have rights to use, and always give proper attribution.
  4. If any relevant accompanying data is submitted to repositories with stated licensing policies, the policies should not be more restrictive than CC BY.
  5. IJAS reserves the right to remove any photos, captures, images, figures, tables, illustrations, audio and video files, and the like, from any paper, whether before or after publication, if we have reason to believe that the content was included in your paper without permission from the owner of the content.

References

Marshall,G.C.and H.W.Ohm 1987 .Yield responses of 16 winter wheat cultivars to row spacing and seeding rate .Agronomy Journal .79:1027-1030

How to Cite

[1]
“Determination of valsartan drug by ion pair complex formation method in tablet form”, IJApSc, vol. 1, no. 2, pp. 56–65, Sep. 2024, doi: 10.69923/851hfy94.

Most read articles by the same author(s)

<< < 1 2 

Similar Articles

1-10 of 14

You may also start an advanced similarity search for this article.