Evaluation of some physiological parameters for Benign Prostatic hyperplasia patients in Diyala province

Abstract

Benign prostatic hyperplasia (BPH) is a non-malignant tumor of the prostate that enlarges prostate tissue and reduces the flow of urine from the bladder. The study aimed to investigate the relationship between certain physiological parameters (body mass, diabetes, smoking, first- and second-degree consanguinity, prostate-specific antigen (PSA), and testosterone (TES)) with the risk of benign prostatic hyperplasia. The study included 100 samples, divided into two groups: the first group consisted of 50 patients, and the second group consisted of 50 healthy controls. The results revealed that the majority of patients were underweight (36.0%), while a small percentage were obese (12.0%). Similarly, the majority of the control group were underweight (60.0%), with only a small percentage being overweight (10.0%). The differences in BMI between the two study groups were statistically significant (p<0.05). There were also significant differences in hemoglobin A1c (HbA1c) levels between the two groups. The cumulative glucose test showed that 44.0% of patients with prostate enlargement had elevated cumulative glucose levels, compared to 0.0% in the healthy control group. The results further indicated that most of the patients had relatives with the disease (46.0%), with 34.0% having second-degree relatives and 20.0% having first-degree relatives affected by the disease. The differences in the percentages of kinship degrees were statistically significant (p<0.05). Additionally, the study found significantly higher PSA levels in patients (11.18±4.06) compared to healthy controls (3.27±1.35). Conversely, testosterone levels were lower in patients (1.74±0.45) compared to healthy controls (6.33±1.80).