A comparative study of the healing effects of sesame oil and TiO2 nanoparticles gel on second-degree burn

Ahmed AL-Shammari; mohanad Alzubadiy; Osamah  Riyadh Abbood; Mohammed Bouskout

doi:10.69923/wr76dn63

A comparative study of the healing effects of sesame oil and TiO2 nanoparticles gel on second-degree burn

Authors

Ahmed AL-Shammari Iraqi Center for Cancer and Medical Genetic Research - Mustansiriyah University Author
mohanad Alzubadiy University of Diyala Author https://orcid.org/0000-0002-4609-1265
Osamah Riyadh Abbood University of Diyala Author
Bouskout Mohammed Cadi Ayyad University Author

DOI:

https://doi.org/10.69923/wr76dn63

Keywords:

nanoparticle, titanium dioxide, Sesamum indicum L., burn wound healing.

Abstract

Burns, a severe form of soft tissue injury, can cause significant damage and, in extreme cases, be fatal. They also lead to considerable mental and emotional distress due to excessive scarring and skin contractures. Despite various treatment methods, burn care remains a challenging medical issue.

In this study, titanium dioxide (TiO₂) nanoparticles were synthesized and characterized using field emission scanning electron microscopy (FE-SEM), revealing particle sizes ranging from 31.52 to 69.08 nanometers.

The impact of biosynthetic nanomaterials and sesame seed oil on burn healing in laboratory rats was investigated. The study compared the effects of a 1% TiO₂ solution and 20% sesame oil on burned skin with a control group of rats having natural skin. Fifteen rats were divided into three groups, each receiving daily treatment for 28 days. The results indicated that the TiO₂ treatment significantly accelerated healing compared to the sesame seed oil group, which had a slower healing rate of 0.12 points per day. The TiO₂ treatment demonstrated a marked improvement in healing speed and effectiveness.

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Author Biographies

Ahmed AL-Shammari, Iraqi Center for Cancer and Medical Genetic Research - Mustansiriyah University

Dr Ahmed Majeed AL-ShammariProfessor:Cancer Research Scientist and Professor of cytopathology at the Experimental Therapy Department at the Iraqi center for Cancer and Medical Genetic Research. I have three main research lines and programs: 1- Cancer virotherapy, which is about using oncolytic viruses to treat cancer as Newcastle disease virus and Measles 2- Creating tumour models as new Iraqi cancer cell lines from Iraqi patients to study the uniqueness of the tumours in Iraq and to use them in the experimental therapies to develop new treatments 3- Stem cell and tissue engineering
mohanad Alzubadiy, University of Diyala

Dr. Mohanad W. Mahdi is Associate Professor at College of Education for Pure Science, University of Diyala, Iraq. He Holds a PhD degree in Biology Science with specialization in and Biotechnology. His research areas are Nanotechnology, Bioinformatics, Biotechnology, Genetics. He has published several scientific papers in national, international conferences and journals. He can be contacted at email: mohanad@uodiyala.edu.iq
Osamah Riyadh Abbood, University of Diyala

Osamah Riyadh Abbood : Assistant Professor in Biological Sciences, Animal Branch. Lecturer at the General Directorate of Diyala Governorate.
Bouskout Mohammed, Cadi Ayyad University

Dr. Bouskout Mohammed completed a Ph.D. in Agro-physiology, Biotechnology and Environment from UCA, Morocco. I'm primarily interested in the impacts of abiotic/biotic factors on the plant microbiota-environment interaction through the investigation of several morphological, physiological,-biochemical, and molecular mechanism attributes, with a specific emphasis on plant nutrient homeostasis and availability as well as their antioxidant responses during microbial symbiosis/development.

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Published

30-09-2024

Issue

Vol. 1 No. 2 (2024)

Section

Research Articles

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How to Cite

[1]

A. AL-Shammari, mohanad Alzubadiy, O. . Riyadh Abbood, and . M. Bouskout, “A comparative study of the healing effects of sesame oil and TiO2 nanoparticles gel on second-degree burn”, IJApSc, vol. 1, no. 2, pp. 102–109, Sep. 2024, doi: 10.69923/wr76dn63.