A comparative study of the healing effects of sesame oil and TiO2 nanoparticles gel on second-degree burn

Authors

  • Ahmed AL-Shammari Iraqi Center for Cancer and Medical Genetic Research - Mustansiriyah University Author
  • mohanad Alzubadiy University of Diyala Author https://orcid.org/0000-0002-4609-1265
  • Osamah Riyadh Abbood University of Diyala Author
  • Bouskout Mohammed Cadi Ayyad University Author

DOI:

https://doi.org/10.69923/wr76dn63

Keywords:

nanoparticle, titanium dioxide, Sesamum indicum L., burn wound healing.

Abstract

Burns, a severe form of soft tissue injury, can cause significant damage and, in extreme cases, be fatal. They also lead to considerable mental and emotional distress due to excessive scarring and skin contractures. Despite various treatment methods, burn care remains a challenging medical issue.

       In this study, titanium dioxide (TiO2) nanoparticles were synthesized and characterized using field emission scanning electron microscopy (FE-SEM), revealing particle sizes ranging from 31.52 to 69.08 nanometers.

        The impact of biosynthetic nanomaterials and sesame seed oil on burn healing in laboratory rats was investigated. The study compared the effects of a 1% TiO2 solution and 20% sesame oil on burned skin with a control group of rats having natural skin. Fifteen rats were divided into three groups, each receiving daily treatment for 28 days. The results indicated that the TiO2 treatment significantly accelerated healing compared to the sesame seed oil group, which had a slower healing rate of 0.12 points per day. The TiO2 treatment demonstrated a marked improvement in healing speed and effectiveness.

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Author Biographies

  • Ahmed AL-Shammari, Iraqi Center for Cancer and Medical Genetic Research - Mustansiriyah University

    Dr Ahmed Majeed AL-Shammari Professor: Cancer Research Scientist and Professor of cytopathology at the Experimental Therapy Department at the Iraqi center for Cancer and Medical Genetic Research. I have three main research lines and programs: 1- Cancer virotherapy, which is about using oncolytic viruses to treat cancer as Newcastle disease virus and Measles 2- Creating tumour models as new Iraqi cancer cell lines from Iraqi patients to study the uniqueness of the tumours in Iraq and to use them in the experimental therapies to develop new treatments 3- Stem cell and tissue engineering

  • mohanad Alzubadiy, University of Diyala

     

    Dr. Mohanad W. Mahdi is Associate Professor at College of Education for Pure Science, University of Diyala, Iraq. He Holds a PhD degree in Biology Science with specialization in and Biotechnology. His research areas are Nanotechnology, Bioinformatics, Biotechnology, Genetics. He has published several scientific papers in national, international conferences and journals. He can be contacted at email: mohanad@uodiyala.edu.iq

  • Osamah Riyadh Abbood, University of Diyala

    Osamah Riyadh Abbood : Assistant Professor in Biological Sciences, Animal Branch. Lecturer at the General Directorate of Diyala Governorate.

  • Bouskout Mohammed, Cadi Ayyad University

    Dr. Bouskout Mohammed completed a Ph.D. in Agro-physiology, Biotechnology and Environment from UCA, Morocco. I'm primarily interested in the impacts of abiotic/biotic factors on the plant microbiota-environment interaction through the investigation of several morphological, physiological,-biochemical, and molecular mechanism attributes, with a specific emphasis on plant nutrient homeostasis and availability as well as their antioxidant responses during microbial symbiosis/development.

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Published

09/30/2024

Issue

Vol. 1 No. 2 (2024)

Section

Articles

License

Copyright (c) 2024 Iraqi Journal for Applied Sciences

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References

Marshall,G.C.and H.W.Ohm 1987 .Yield responses of 16 winter wheat cultivars to row spacing and seeding rate .Agronomy Journal .79:1027-1030

How to Cite

[1]
“A comparative study of the healing effects of sesame oil and TiO2 nanoparticles gel on second-degree burn”, IJApSc, vol. 1, no. 2, pp. 102–109, Sep. 2024, doi: 10.69923/wr76dn63.

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