Effect of Pregnyl (HCG) on Histological Structure of Testes in Albino Mice

Authors

  • Hassan Muhaimed Ministry of Education Author
  • Thekra Atta Ibrahim University of Diyala Author

DOI:

https://doi.org/10.69923/bgm1zs71

Keywords:

Testis, Sertolic cells, Pregnyl (HCG), Seminifrous tubules, Leydig cells

Abstract

Pregnyl is a placental hormone, produced mainly during the entire period of pregnancy, making it the vital sign for detecting pregnancy. The current study shed light on the effect of pregnyl on the histological structure of testes in Albino mice. The study included 15 mice, and the animals were divided into two groups. The first group included five mice, and the second group included ten mice. They were placed in separate cages with continuous monitoring and cleaning throughout the study. The first group was injected with Pregnyl at a concentration of 0.1 mg/kg and the second group at a concentration of 0.2 mg/kg for a period of 30 days. After the end of the experiment, the animals were sacrificed, dissected, and their testicles were removed for the purpose of histological study. The outcome of this study shows that the animals in the two empirical groups treated with Pregnyl showed changes in thickness of seminiferous tubules of the testis wall and their shrinkage, as their manifestation became wavy and offbeat. Furthermore, atrophy was noted in a few of the seminiferous tubules, as well as the sloughing and exhaustion of some germ cells and their accumulation in the lumen of seminiferous tubules. Additionally, degeneration was observed in some Sertolic cells.

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Author Biographies

  • Hassan Muhaimed, Ministry of Education

    Salam Maseer Juma’a is a MSc. Student in Department of Biology – College of Education for Pure Science – University of Diyala. he can be contacted at email: salammsser92@gmail.com

  • Thekra Atta Ibrahim, University of Diyala

    Dr. Thekra Atta Ibrahim is a professor at the College of Education for Pure Science, University of Diyala, Iraq. She received her B.Sc. degree and M.Sc. degree in biology science from the University of Diyala, Iraq. She holds a PhD degree in biology Science with a specialization in Histological Analysis Tissue Preparation Paraffin Embedding Anatomic Pathology Immuno-histology Immunocytochemistry Tissue Fixation Tissue Dissection Cryostat Sectioning and Ultrastructure. Her research areas are embryology and histology. She has published several scientific papers in national, international conferences and journals. She can be contacted at email: thekraatta@uodiyala.edu.iq.

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Published

09/30/2024

Issue

Vol. 1 No. 2 (2024)

Section

Articles

License

Copyright (c) 2024 Iraqi Journal for Applied Sciences

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References

Marshall,G.C.and H.W.Ohm 1987 .Yield responses of 16 winter wheat cultivars to row spacing and seeding rate .Agronomy Journal .79:1027-1030

How to Cite

[1]
“Effect of Pregnyl (HCG) on Histological Structure of Testes in Albino Mice”, IJApSc, vol. 1, no. 2, pp. 86–92, Sep. 2024, doi: 10.69923/bgm1zs71.

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