Immunological and Metabolic changes in Iraqi Women Patient with Graves' disease

Authors

  • Zeena hamood University of Diyala Author
  • Zainab Khidhair Hussain University of Baghdad Author

DOI:

https://doi.org/10.69923/0ck55q34

Keywords:

Grave’s disease, C-reactive protein, Lipid profile

Abstract

Graves' disease, a common cause of hyperthyroidism, affects middle-aged individuals, affecting lipid metabolism. Risk factors include genetic, environmental, and immunological factors. The aim of the study was to examine the possible correlation between certain blood biomarkers in individuals with Graves' disease before and after undergoing therapy with radioactive iodine (RAI). Sixty grave’s disease patients, 30 of whom received radioiodine therapy, in addition to 30 healthy people as control with age range of (25-60) years old were enrolled in this study through their presence at the AL-Amal National Hospital for nuclear medicine in Baghdad. Blood samples were collected to evaluate the level lipid profile, C-reactive protein, complete blood count, sodium and calcium. Results showed highly significant (P≤0.01) decreased in lipid profile parameters and a significant increasing in C-reactive protein level in both groups, before and after treatment, but no relation was found between GD and sodium and calcium. Thyroid dysfunction had an obvious impact on lipid metabolism. Grave's disease decreases lipid levels and increases body metabolism. Also increase an inflammation in body leading to high CRP levels in patients. No relationship was found between electrolyte elements.

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Author Biographies

  • Zeena hamood, University of Diyala

    Zeena Mzahim Hamood: University of Baghdad, college of science, biology department. Work location: Presidency of Diyala University.

  • Zainab Khidhair Hussain, University of Baghdad

    Zainab Khidhair Hussain: Doctorate degree. General specialty: Zoology.Specialization: physiology

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Published

12/30/2024

Issue

Vol. 1 No. 3 (2024)

Section

Articles

License

Copyright (c) 2024 Iraqi Journal for Applied Science

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References

Marshall,G.C.and H.W.Ohm 1987 .Yield responses of 16 winter wheat cultivars to row spacing and seeding rate .Agronomy Journal .79:1027-1030

How to Cite

[1]
Z. hamood and Z. . Khidhair Hussain, “Immunological and Metabolic changes in Iraqi Women Patient with Graves’ disease”, IJApSc, vol. 1, no. 3, pp. 50–55, Dec. 2024, doi: 10.69923/0ck55q34.

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